Question

3. Question 3 (Multiple Hypothesis Testing)

The dataset q3 pualues.csv stores two hundred p-values for multiple testings.

Consider conducting large-scale hypothesis testing to control the FWER or

FDR.

(a) Conduct Bonferroni's correlation, Holm's procedure, and Benjamini Hochberg's

procedure under a = 0.05 and q = 0.05 then compare the results.

(b) Overlay the not rejected and rejected p-values, and the corresponding

criterion curve in a plot for Bonferroni's correlation, Holm's procedure,

and Benjamini Hochberg's procedure separately. Denote the not re-

jected and rejected p-values by different colors. (You can use log-scale

for demonstration and the plots in our lecture notes are good examples.)

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