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ONLY THE PDF PROVIDED, NO OTHER SOURCES. Reading guidelines for paper discussion What is the overall question that the scientists are trying to address in this paper? Introduction What type of

organism is Vibrio cholerae? What disease does it cause? How is it transmitted? What are the symptoms? What is IgA? What is its role in our immune system? Which V. cholera antigens does our immune system produce antibodies against? What is the role of each of these antigens in a cholera infection? Methods What is a cohort? What is a case-control study? What is an index case? Who were enrolled in the study (how were they chosen?) Results: For each table and figure answer the following: What is the purpose of this figure/Table? What type of information/samples/data were collected from the participants, why and how? What does it show? (What is the overall result?)

Fig: 1