Select words or phrases from the drop down menu to complete the sentences provided. The innate adaptive immune system plays key roles in activating and regulating adaptive immune responses. dendritic cells

are key mediators of these roles. They bind pathogens at epithelial layers and deliver them to secondary lymphoid organs such as lymph nodes. After activation induced by TLR signaling, they present peptides from processed antigen to activate naïve CD4 and CD8 T-cells. Depending on the pathogen and the PRRS to which it binds, dendritic cells are activated to produce certain cytokines. Answer 1: adaptive Answer 2: dendritic Answer 3: secondary Answer 4: TLR signaling Answer 5: T-cells Answer 6: cytokines