2. The reaction involves two NADH-dependent enzymes: one reduces a ketone to an alcohol and one reduces a carboxylate to an alcohol.Assume that the binding of substrates to each enzyme

is very sensitive to the structure and stereochemistry of the entire substrate. By using the isotopically labelled (^14 C) substrate shown below, one can deduce which enzyme acts first. Considering the 1:1 mixture of products formed below, deduce the order of the enzyme reactions and draw the intermediate. Explain briefly

Fig: 1

Fig: 2