Question

3. [7 pts] At the onset of moderate exercise, the tensing of the muscles involved plus an increase in venomotor tone produces a decrease in venous compliance, thereby raising Pms- Sympathetic

stimulation leads subsequently to an increase in heart rate by 40% and doubling Qc,max from its normal value. Vaso- and venomotor tone also increased by 40%. Then, local vasodilation of the muscular vascular beds produces a marked decrease in peripheral resistance by 40% in both arterial and venous vasculatures. The following are the parameter values under normal resting conditions: f CD Cs Qcmax РА Ppl RA Ry CA Cy V = 72 beats min¹² = 0.035 L mmHg ¹ = 0.0007 L mmHg¹ 13 L/min = 100 mmHg = -4 mmHg = 19.2 mmHg min L¹¹ = 0.4 mmHg min L²¹ = 0.028 L mmHg ¹ = 0.5 L mmHg¹¹ = 3.7 L (total blood volume that exerts stress, aka stress volum) a) [5 pts] Use MATLAB to plot the cardiac output and venous return curves during moderate exercise on the same plot as the normal curves (see hold function). Add legend to the plot (see legend function to indicate which graph is Qc or QR and under which condition - normal or exercise. b) [1 pt] From the plot, determine the steady-state operating value of cardiac output if an increase in heart rate and Qc,max are the only responses to moderate exercise. c) [1 pt] From the plot, determine the steady-state operating value of cardiac output when heart responses change with the systemic circulation. d) [1 pt] Copy and paste the MATLAB code you used in this question. You may take a picture of your MATLAB script, but please make sure that the code is clearly readable from the image.

Fig: 1