Clinical Drug Development

Questions & Answers

18F-Fluoroestradiol PET-Imaging in Cancer-Clinical evaluation Describe the hypothesis of the clinical trial. What phase? Dosimetry? Proof of concept? Proof-of-pharmacology? • Describe the purpose of the trial in your report. • Describe the design. How many subjects? Scanning protocol? Inclusion criteria? Healthy volunteers or patients with a diagnosed condition? Control groups? What were the results and how should the results be interpreted? • How is the tracer used in the clinic today?

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