17. Use the DNA sequence 5'-ATCTCCTGGTAA-3' to demonstrate the effect of each type of mutation on the resulting polypeptide sequence. Include sequences for DNA, mRNA, and polypeptide. a) Missense mutation b) Frameshift mutation Considering the following DNA sequence: 3' CCGTACCCTGTATAAAAC - 5' a. Write the complementary DNA strand that would be produced in replication (A/1): b. Write the complementary mRNA strand that would be produced in transcription (A/1): c. What is the sequence of amino acids that would result from translation of the mRNA sequence? (A/1)

Lab Report 2 on Genetics 1. Table 1 from the Simulated ABO & Rh Blood typing handout activity on page 8.

2. Describe the conditions of erythroblastosis fetalis and what happens when sensitization to Rh antigens occurs.

4. Describe who can each blood type give blood to and receive blood from.

7. In order for a population to remain in Hardy-Weinberg equilibrium, what conditions must be met?

8. Using Hardy Weinberg, if there is a class of 19 students and 15 students have a widow's peak, what are the frequencies of each genotype? (Use human genetic taste paper set)

9. Complete a dihybrid cross of corn with the two traits of height (tall and short) and color (green and albino) (use the population genetics handout).

Suppose an individual had a mutation in their gene that codes for the production of DNA polymerase I. What issues would this individual experience? Explain by referring to specific concepts learned in class.

Based on the strand of DNA below, determine the amino acid sequence that would be produced. Show your work!

While studying for your molecular genetics test, your friend says that during translation, the polypeptide chain is always located in the P site of the ribosome. Is your friend correct? Refer to the process of polypeptide production in the ribosomes to explain.

2. Complete the following chart by indicating whether the genes of the lac operon are expressed (=ON) or repressed (= OFF) under the following conditions

1. Why do some point mutations in DNA affect protein structure while others do not? Why do some mutations affecting protein structure have mild effects on phenotype, while others have very serious (or life-threatening) effects? Explain this phenomenon in terms of eukaryotic gene structure, the genetic code, and protein structure.

4. Which of the following sequences (on one strand of a double-stranded DNA molecule) is likely to be a cleavage site for a restriction endonuclease? Briefly explain your answer. a. CGTACCb. ATGTCGc. GATATGd. TGCGCAe. TGGCCG