2C. Examine the area of the gp120 protein where Chemical Y2E is associated for hydrophobicity and charge.

Describe what you observe citing evidence from the iCn3D depiction. Name a specific amino acid

substitution (using amino acid numbering in image 8FM5) that would be very likely to make HIV resistant to

Chemical Y2E. Explain your reasoning (including why replacing that particular amino acid would have an

effect and why the substitution that you are suggesting would have an effect).