Question

5. Please propose a reasonable mechanism for each of the following Pd-

catalyzed reactions and explain any regio- and diastereoselectivities observed.

Catalysis: Tutorial 3

a.

b.

MeO₂C.

MeO₂C

NBoc

Br

Me

Pd(OAc)2, PPh3 (cat.)

Pd(PPH3)4 (cat.)

El N, MeCN

BocN

MeO₂C.

MeO₂C

Me

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