ar

5. An aminophenol catalyst c has been reported to promote enantioselective

allylation of N-phosphinoylimines as shown below. Given that this reaction.

proceeds, through transition state I, please indicate the activation concept(s)

involved in the catalytic system.

Catalysis: Tutorial 1

Ph

NPOPh₂

e

L₂B-OMe

Me₂N-

O

To-do

-B

Me

Me

t-Bu

R

N=H

OF

Me

Me

-Ph

Ph

t-Bu

OH

c (3 mol %)

e

L₂B-OMe

Me₂N-

i-Pr

NaOf-Bu (2.5 mol %)

MeOH (2.5 equiv.)

toluene, RT, 4 h

11

NM₂

t-Bu

R

IR

-Ph

Ph

Notifications

NPOPH₂

Ph

95% yield, 96.5:3.5 e.r.

major

isomer

K

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