Question

Biochemistry

The Delta Plus variant of SARS-CoV-2 has been found to have an amino acid substitution in the spike protein known as K417N. The spike protein is considered to be how the viral particle attaches to the host cell for infection. Based on your knowledge of amino acid side chain chemistry, speculate how this amino acid substitution (i.e. N replaces K at position 417) could lead to an altered potentially improved interaction with the host protein receptor. Your answer should include the following:


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