This is a question about the Krebs cycle Carbon is introduced to the cycle from acetyl co enzyme a (acSCoA) which citrate synthase reacts with oxaloacetate to provide citrate citrate

has prochiral center indicated with * below . The two new carbons (from ACSCOA) are introduced as the pro-S group in citrate this the group to the left or right as drawn above? In order for acSCoA to react with oxaloacetate the enzyme must first de protonate the acscoa given information which substrate ( AcSCOA or oxaloacetate ) is reacting as the nucleophie the electrophile explain your reasoning c. Explain why the protons of the methyl group in ACSCOA are acidic. OMOThe next two reactions are catalyzed by aconitase: what type of isomerism most accurately describes the relationship between citrate and isocitrate e. Provide stereochemical descriptors (R, S, E, and Z) for all stereochemical elements present in aconitate and isocitrate. f. What is the identity of the molecule X? g. Consider the reaction of citrate to aconitate. Draw three mechanisms (E1, E1cb,and E2) for the reaction of citrate to aconitate.[6]