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Q1:3. What is the human Genome Project? What is Precision medicine?See Answer
Q2:Assume the mating of two dogs from different breeds that both show an excessive bleeding disorder. In one breed, the condition is an autosomal recessive, and in the other a sex-linked recessive. The dogs used are an affected male Lab and an affected female Doberman. The progeny resulting from the mating are: 1. All normal females 2. All affected males Which breed has the sex-linked disorder and what is the genotype for that breed at both loci?See Answer
Q3:In this assignment, you will be researching a disease/illness linked to genetic mutation, and therefore, gene expression. You will also be investigating how different methods of genetic screening can help in the prediction and diagnosis of your selected disease, as well as how gene therapy could potentially be used to treat your disease. When selecting your disease, you should select a disease that is developed at some point during a person's life, as opposed to a congenital disease (something that a person is born with). You should also not select a disease with a simple inheritance pattern (ie. sickle cell anemia). Choose a disease that has multiple genes interacting and is also influenced by lifestyle/environment. In other words, don't choose a disease that you are either guaranteed to have or not have.See Answer
Q4:For RNA polymerase to begin DNA transcription, which nitrogenous base sequence is known as the promoter site? UAG AAAA TATA AUCSee Answer
Q5:Which of the following is an example of a coding strand of DNA? 3¹-ATCGCCCAG - 5¹ 5¹-ATCGCCCAG-3' 3'-AUCGCCCAG-5¹ 5¹-AUCGCCCAG - 3¹See Answer
Q6:Which of the following is true of mRNA? It is oriented in a 3'- 5' direction It is complimentary to the coding strand of DNA It is identical to the coding strand of DNA None of the above are trueSee Answer
Q7:Which of the following is an example of a section of a strand of mRNA? 3¹-ATCGCCCAG-5' 5-ATCGCCCAG-3¹ 3-AUCGCCCAG-5¹ s'-AUCGCCCAG-3'See Answer
Q8:If a point mutation occurs in a template strand of DNA, will that mutation also be seen in the nitrogenous base code of the mRNA? Yes No It dependsSee Answer
Q9:A section of mRNA has the sequence 5'-...GCCAUAGAC...-3. What was the code of the original coding strand of DNA? 5'-...GCCAUAGAC....-3' 5'-...GCCATAGAC....-3' 3-...GCCAUAGAC...-5' 3-...GCCATAGAC....-5'See Answer
Q10:A coding strand of DNA has the nitrogenous base sequence TACGGT. What would the corresponding mRNA sequence be? OTACGGT OUACGGU QATGCCA AUGCCASee Answer
Q11:Based on the following strand of mRNA, what was the original template strand of DNA? 5'-AUCGCGCCA-3¹ 5'-ATCGCGCCA - 3¹ 3'-ATCGCGCCA-5' 3'-TAGCGCGGT - 5' 5'-TAGCGCGGT-3'See Answer
Q12:A section of a template strand of DNA has the nitrogenous base sequence CGGTCA. What would the corresponding mRNA sequence be? CGGTCA CGGUCA GCCAGT GCCAGUSee Answer
Q13:Which of the following is a modification that needs to be made to pre-mRNA before it can exit the nucleus? Addition of a poly-A tail on the 5' end Addition of a guanine cap on the 3' end Splicing out of introns All of the aboveSee Answer
Q14:Which of the following is true of RNA primers? They are only used in building on the lagging strand There are numerous RNA primers used when building on the leading strand Once replaced, they are known as Okazaki fragments They create attachment points for the DNA polymerase to attach to and begin laying down nucleotides in a 5'--> 3' directionSee Answer
Q15:Which of the following is true of DNA polymerase? It can only read DNA in a 3's 5' direction. It can only build a new strand of DNA in a 3' à 5' direction It does not require helicase to separate the two strands of DNA It is used in DNA transcriptionSee Answer
Q16:Which of the following DNA polymerases is responsible for replacing RNA primers with DNA nucleotides? DNA polymerase I DNA polymerase II DNA polymerase III All of the aboveSee Answer
Q17:Which of the following enzymes is responsible for creating phosphodiester bonds between Okazaki fragments and recently replaced primers? DNA polymerase 1 DNA polymerase II RNA polymerase DNA ligaseSee Answer
Q18:Which of the following are DNA polymerases responsible for? Laying down complimentary nucleoside triphosphates in the complimentary strands Replacing RNA primers with DNA nucleotides Checking the complimentary strands for errors All of the aboveSee Answer
Q19:Which of the following point mutations could lead to a frameshift mutation? Insertion Substitution Inversion MissenceSee Answer
Q20:For the coding of a particular protein, an individual's gene is the correct length of nitrogenous bases, their mRNA is the correct length, however their amino acid sequence is short by 30 amino acids. Which type of mutation is likely responsible? Silent mutation Frameshift mutation Nonsense mutation None of the aboveSee Answer

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