Which of the following are DNA polymerases responsible for?

Assume the mating of two dogs from different breeds that both show an excessive bleeding disorder. In one breed, the condition is an autosomal recessive, and in the other a sex-linked recessive. The dogs used are an affected male Lab and an affected female Doberman. The progeny resulting from the mating are: 1. All normal females 2. All affected males Which breed has the sex-linked disorder and what is the genotype for that breed at both loci?

Based on the following strand of mRNA, what was the original template strand of DNA? 5'-AUCGCGCCA-3¹ 5'-ATCGCGCCA - 3¹ 3'-ATCGCGCCA-5' 3'-TAGCGCGGT - 5' 5'-TAGCGCGGT-3'

A section of mRNA has the sequence 5'-...GCCAUAGAC...-3. What was the code of the original coding strand of DNA? 5'-...GCCAUAGAC....-3' 5'-...GCCATAGAC....-3' 3-...GCCAUAGAC...-5' 3-...GCCATAGAC....-5'

Suppose an individual had a mutation in their gene that codes for the production of DNA polymerase I. What issues would this individual experience? Explain by referring to specific concepts learned in class.

Which of the following is true of RNA primers? They are only used in building on the lagging strand There are numerous RNA primers used when building on the leading strand Once replaced, they are known as Okazaki fragments They create attachment points for the DNA polymerase to attach to and begin laying down nucleotides in a 5'--> 3' direction

While studying for your molecular genetics test, your friend says that during translation, the polypeptide chain is always located in the P site of the ribosome. Is your friend correct? Refer to the process of polypeptide production in the ribosomes to explain.

Which of the following is a modification that needs to be made to pre-mRNA before it can exit the nucleus? Addition of a poly-A tail on the 5' end Addition of a guanine cap on the 3' end Splicing out of introns All of the above

17. Use the DNA sequence 5'-ATCTCCTGGTAA-3' to demonstrate the effect of each type of mutation on the resulting polypeptide sequence. Include sequences for DNA, mRNA, and polypeptide. a) Missense mutation b) Frameshift mutation Considering the following DNA sequence: 3' CCGTACCCTGTATAAAAC - 5' a. Write the complementary DNA strand that would be produced in replication (A/1): b. Write the complementary mRNA strand that would be produced in transcription (A/1): c. What is the sequence of amino acids that would result from translation of the mRNA sequence? (A/1)

Which of the following is true of mRNA? It is oriented in a 3'- 5' direction It is complimentary to the coding strand of DNA It is identical to the coding strand of DNA None of the above are true

In this assignment, you will be researching a disease/illness linked to genetic mutation, and therefore, gene expression. You will also be investigating how different methods of genetic screening can help in the prediction and diagnosis of your selected disease, as well as how gene therapy could potentially be used to treat your disease. When selecting your disease, you should select a disease that is developed at some point during a person's life, as opposed to a congenital disease (something that a person is born with). You should also not select a disease with a simple inheritance pattern (ie. sickle cell anemia). Choose a disease that has multiple genes interacting and is also influenced by lifestyle/environment. In other words, don't choose a disease that you are either guaranteed to have or not have.