Bioinormatics
Your professor gives you a population of freshmen students at UCLA, and asks you to compute a 99% pivotal Cl for their mean high school GPAS. What would you do?
a. I would ask a classmate and do whatever they tell me to
b. Cls make sense when we have samples and not the whole population. This is an absurd task and I would respectfully let my professor know that this is not reasonable
c. I would respectfully do what my professor wants because want an A in this class
d. I would use the bootstrap resampling with replacement of the population 10,000 times and compute a pivotal 99% Cl from the histogram of such mean GPAS
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Bioinormatics
Suppose a posterior probability was 0.05 for a COVID test. What would be your conclusion?
O c. If you had a positive antibody test for COVID, there is a 5% chance that you actually had COVID
O b. Every 5th person has COVID and you are one of them
O a. If you had a 5% chance of testing positive, you will have COVID
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Bioinormatics
Compute a posterior probability of you having the COVID-19, i.e., P(COVID|+), given that you tested + to the antibody test. Assume sensitivity = specificity = 90% and prevalence as you computed inQ29.
O a. 0.0625O b. 0.026367O c. 0.03967O d. 0.0397O e. 0.0497O f. 0.00587
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Bioinormatics
Drag and drop the various terms into the correct boxes to compute the posterior probability of you having the COVID-19.
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Bioinormatics
Suppose there are 115,192 confirmed COVID-19 cases in California with a population of 39.5 million people, what is the prevalence?
O a. 3%O b. 33.333%O c. 3 out of every 1000 peopled. 3 out of every 100 people
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Bioinormatics
Which of the following is/are synonymous with P(COVID-19)?
O a. PrevalenceO b. Specificityc. 1- SpecificityO d. Sensitivity
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Bioinormatics
Which of the following is/are synonymous with P(+ | COVID-19)?
b. Prevalence
Oc.Specificity
O d. 1- Specificity
O a.Sensitivity
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Bioinormatics
Which of the following is/are synonymous with posterior probability, also known as the positive predictive value? Select all that apply.Note: Wrong answers result in 50% points deduction on this question. Please choose wisely.
O b. Sensitivity
a. Prevalence
O c. Bayesian probability
d. Conditional probability, P(COVID-19 | +)
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Bioinormatics
As you must know, an alpha cutoff of 0.2 is unheard of. In which of the following circumstances would you accept such a high alpha due to high social cost of a false negative (despite the increase in likelihood of false positives due to high alpha)?
O c.Convicting a person accused of shoplifting
O b. Diagnosis of colon cancer
Hiring a fraudulent real estate agentO a.
O d. Diagnosis of engine failure
O e.Detecting saltiness in seafood
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Bioinormatics
Why do you use nested for-loops when you compute power using the bootstrap approach?
O d. This is how we create a phantom world
O aThe inner loop computes a p-value, while the outer loop simulates a number of phantom studies
O b. To compute power twice and make sure it is done correctly!
O c. To enable simulation of n^n studies so we have a high power study
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Bioinormatics
Which of the following is/are true statement(s) about the power of a study? Select all that apply.Note: Wrong selection results in points deduction on this question. Please choose wisely
O d. Given an effect size, increasing the variability of samples increases power
O a.Given an effect size, increasing the sample size increases power
O b. Given an effect size, increasing alpha cutoff increases power
c. Power is invariant to the magnitude of effect size for a given alpha cutoff and sample size
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