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of rounds experience at the top center of page 1./n kaléo Together, We Build Solutions for Life Okaleo, Inc. 2020 For Educational Purposes Only. Not to be distributed beyond intended audience. CC-US--0058 kaleopharma.com Who is kaléo? Kaléo is a fully integrated pharmaceutical company with strong infrastructure and a full suite of competencies to develop and commercialize innovative products The Greek meaning of Kaléo: to answer a calling or have a purpose Mission Statement Invent, manufacture and commercialize life-transforming products that empower patients and families to live fuller, bolder lives. And Develop innovative solutions that support the healthcare provider-patient relationship, unleashing access to life transforming products. Key Competencies Drug/Device Product Development & Human Factors Engineering Quality & Regulatory Medical Affairs & Pharmacovigilance Global Supply & Manufacturing Commercialization Business & Data Analytics IP Portfolio Management Okaleo, Inc. 2020 For Educational Purposes Only. Not to be distributed beyond intended audience. CC-US--0058 kaleopharma.com 2 G The kaléo Way... Innovation & Excellence Winning Teamwork Professional Accountability Mutual Respect Personal Integrity Purposeful & Passionate Culture Okaleo, Inc. 2020 For Educational Purposes Only. Not to be distributed beyond intended audience. CC-US--0058 kaleo kaleopharma.com. 3 ● ● ● kaléo Overview Founded by Patients Leading innovative patent-protected auto-injector platform and technologies Five FDA Approved Products AUVI-QⓇ (epinephrine injection, USP) Auto-injector 0.15 mg and 0.3 mg (2012) 0.1 mg dose (2017) ● ● EVZIO® (naloxone Hcl, injection) Auto-injector 0.4 mg approved (2014) - no longer marketed 2 mg approved (2016) ● Strong Management Team with Broad Expertise 200+ FTES Support Development, Manufacturing, and Commercialization Well Capitalized and Sustainable Business Auvi- de g se PAL device up from is Auvi-q epinephrine injection, USP gauto-injector peop FOR ALLER EMERGENCIES in swing 50 Indic Evro MC6000 PULL DEVICE UP FW 1502 Auvi-Q Cem Okaleo, Inc. 2020 For Educational Purposes Only. Not to be distributed beyond intended audience. CC-US--0058 Pull device ap from this case Tengle-st SOSTE Auvi-Q epinephrine injection, USP 0.3 mg ato-injector FOR ALLERGIE EMERGENOES in patiects sweighing over b Evzio naloxore HCI Injection. USP #4199 Makr forese found side on device FRONT коп INFPICERIES INDIENGES SUCH AS SUSPECTED OSPENSE Laws Ichachkrbore freddocks Re Auvi-Q ad 300 1646 Pvd device up fram is case Auvi-Q ernestina hestion 5 05px ge-ca mirat el p FRA EVERES wp10060 oslo fede FRONT Evzio PULL DEVICE UP 10 Evzio naloxone HCI injection, USP zmouto Injector USE FOR OPIOID EMERGENCIES SUCH AS SUSPECTED OVERDOSE Seak Crargey Nescalfacies totrawersker efendirace ondata 3936 Scho kaleopharma.com 4 Usability, Quality & Reliability are Systematically Built into kaléo Products Strong Ubiquitous Quality and Compliance First Culture Robust Design Controls and Quality Systems World-Class Supply Chain and Oversight State-of-the-Art Automated Manufacturing Systems Continuous Improvement through Feedback Loops = Exceptional Product Quality and Reliability Every auto-injector must work every time Okaleo, Inc. 2020 For Educational Purposes Only. Not to be distributed beyond intended audience. CC-US--0058 kaleopharma.com. 5