Physiology
Questions & Answers
2. your topic 1. The Physiology of Extreme Environments • Topic: Respiratory responses in high-altitude climbers: Python L et al. 2016. Physiological characteristics of elite high-altitude climbers. 3. Preparing your assessment You should read the scientific paper that you have been assigned in detail (and possibly any papers that may have cited this work subsequently). Your scientific article should address the following aspects of the physiological discovery (ie the mechanisms of the phenomenon/system): • Describe the key features of the phenomenon/system and the rationale for the study • Explain how these findings fit into the wider picture, including how the latest findings may help us to prevent/alleviate or treat pathophysiological conditions associated with this system
GUIDELINES: For your initial post you must: • Identify key anatomical features of your selected organ system, list them, and describe each briefly. • Identify key physiological functions of the organ system and its key histology features (i.e., the cell and tissue types found in this organ system) that enable its physiological functions. • List these features with a brief description of each physiological function and cell/tissue type. • List 2 interesting facts and 2 health issues related to this organ system. Include a brief description of each one. • List your research sources for the initial post such as valid websites (CDC, etc.), and links to the scientific articles, but NOT Wikipedia.
Highlight and explain the key findings/data from the research article. . Identify and explain 3 to 4 key findings/results which best address the aim of the paper. Each key finding may be represented by either a single panel from a figure e.g. 1A, several panels from a figure, a full figure, full table or indeed part of a table, if appropriate. Being selective in your choice of data presentation is key i.e. consider carefully if all panels from a figure are essential or all the content of a table is required, for example. What did the researchers conclude from the results data?
3. Regarding critical analysis, highlight and explain some good points and points for improvement e.g. limitations, within the research? HINTS: Consider if the appropriate models/methodology are used. Did the authors interpret the data correctly? Suggest how experimental design could be improved/modified -Use the resources provided in the module for tips and guidance on critical analysis. Try to use supporting evidence to substantiate your points It is better to have fewer sound points explained fully than many just mentioned or listed and superficially covered.
Which of the following cell types can be used in cell therapy to treat macular degeneration?
Myasthenia gravis (MG) is an autoimmune disease that interferes with synaptic transmission and leads to muscle weakness. In your mini-review, describe how neuromuscular transmission is affected by autoantibodies in MG and mention one of the available treatment options.
Red blood cells (RBCs) contain 0.9% NaCl and no urea in the intracellular fluid (ICF). Assuming the cell membrane of RBCs are impermeable to NaCl and permeable tour ea, predict what would happen if the extracellular fluid (ECF) contained 18.0% urea. What term describes the osmolarity of the cell? What term describes the tonicity of the solution?
